Applications Vaccixcell

Indications

VacciXcell bioreactors have been used for various applications, including the production of vaccines against different diseases and indications.

Hepatitis A virus (HAV) is the virus the causes the disease of the same name, Hepatitis A, which is an inflammation and impairment of the liver. HAV is highly contagious and can be transmitted through drinking of infected water, consumption of infected food products, and close contact or intercourse with an infected individual. Improved sanitation, proper hygiene and immunization have greatly helped decrease the number of HAV cases today.

VacciXcell’s tide motion bioreactor is currently being used in the development and production of an HAV vaccine.

 

Sources:

Existing Customers

Hog cholera is another name for the classical swine fever, which is a highly contagious viral disease in pigs and wild boars. The severity of the disease varies with the virus strain, pig age and herd immunity. The disease is caused by a virus commonly known as the classical swine fever virus or CSFV, which is a member of the virus family Flaviviridae. The disease is highly contagious and can be transmitted between pigs through excretions, secretions, blood and tissue. Although the disease cannot affect humans, it is of great concern, as this leads to large economic losses.

VacciXcell’s tide motion bioreactor system has been and is currently being used in the development of a vaccine against the hog cholera virus, using various cell lines.

 

Sources:

Existing Customers

Rabies is a viral disease that is transmitted from animals to humans through scratches and bites from a rabid animal, with dogs being the reported cause of the majority of rabies-related deaths. Rabies can be prevented by immunization of the animal or people; however, this is often neglected in developing countries due to immunization costs. Research and development is continuously being performed to decrease the production costs of vaccine against rabies.

VacciXcell’s tide motion bioreactor system is currently being used in the development of a low cost production of vaccine against rabies.

 

Sources:
Existing Customers

EV71 or Enterovirus 71 is one of the pathogens that causes hand, foot and mouth disease (HMFD), which is a disease that causes sores in and on the mouth, foot, hands and sometimes the buttocks. HMFD most commonly occurs in children, but it can still occur in adults. HMFD is a minor illness and the risk of transmission may be greatly lowered through proper hygiene.

VacciXcell’s tide motion bioreactor system is currently being used in the development of a vaccine against EV71 using a mammalian cell line.

 

Sources:

Existing customer

IBDV or Infectious Bursal Disease Virus is the common name for the virus, which causes Infectious Bursal Disease (IBD). IBDV is a member of the family Bimaviridae, particularly of the genus Avibimavirus. IBD, also known as Gumboro Disease, is a highly contagious disease amongst domestic chickens and its severity varies with the virulence of the virus strain and the age of the chicken. IBD causes immunosuppression and increased susceptibility to secondary infections. Although it cannot infect humans, IBDV is still of great concern, as the high mortality rate in chicken can lead to large economic losses.

VacciXcell’s tide motion bioreactor system is currently being used in the development of a vaccine against IBDV using a mammalian cell line.

Sources:

Existing Customers

Japanese Encephalitis (JE) is a viral disease that infects both humans and animals and is caused by a flavivirus, more commonly known as the Japanese Encephalitis Virus (JEV). JE causes inflammation of the membrane surrounding the membrane; although more prominent in children, JE can still occur in adults. JE is transmitted by the mosquitos, mainly the Culex species, and is contained within Asia and the West Pacific Region.

VacciXcell’s tide motion bioreactor system is currently being used in the development of a vaccine against JEV using a mammalian cell line.

Sources:
Existing Customers

Influenza, more commonly known as the flu, is a disease caused by the influenza virus that attacks the respiratory system. Influenza can affect both humans and animals, depending on the strain. The strain of influenza virus also affects severity, with some strains causing flu that can subside naturally, while some can cause serious epidemics. Regardless of the severity of the strain, influenza cases can be reduced and prevented through immunization.

VacciXcell’s tide motion bioreactor system has been and is currently being used for the development of vaccines against different strains of the influenza virus, using different mammalian cell lines.

 

Sources:
Existing Customers