Applications Vaccixcell

Hepatitis A

Description

Hepatitis A virus is a liver disease causing virus that is rarely fatal but can have debilitating symptoms. Unlike Hepatitis B or Hepatitis C, Hepatitis A virus does not cause chronic liver disease but rather causes acute liver failure which is often fatal.

Hepatitis A virus is often transmitted to an unimmunized person through ingestion of unsafe food or water that has been contaminated with the feces of a contaminated person. Hepatitis A virus has a tendency of cyclical recurrence as well as sporadically cause epidemics worldwide.

Treatment and Prevention

No specific cure is currently available for hepatitis A. During recovery, healthcare facilities rely on managing the symptoms rather than addressing the actual diseases. Recovery from hepatitis A usually takes several weeks or months.

Vaccination is acknowledge as the best method of prevention for hepatitis A

Vaccine Production

Hepatitis A virus can be cultured in-vitro through propagation in a variety of mammalian cell lines. VacciXcell's tidemotion bioreactor is the best truly linearly scalable bioreactor currently available in the market for culturing adherent cells, including MDBK, MDCK and Vero cells. Using this technology, it is easier to scale up and achieve production scale for vaccine production.

To learn more about Tidemotion Bioreactors

 

REFERENCE:

Hepatitis A www.who.int