News Release VacciXcell

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Understanding Vaccines: Attenuated vs Inactivated

 

Mar 17, 2017

 

LIVE

Attenuated vaccines contain live viruses albeit "weakened". These viruses live such that they can induce an immune response but not strong enough to cause disease to the host

VS

KILLED

Inactivated vaccines contain inactive or "killed" viruses. The viruses were inactivated using either chemical or physical processes but retain their composition thus still allowing them to induce an immune response

LIMITED REPLICATION

Viruses used for attenuated vaccines are passed in a cell line that is very different from the intended recipient. By doing so, the virus would mutate to be very efficient in reproducing in the new cell line while losing its capability to replicate in the old cell line

VS

NO REPLICATION

Since the viruses for inactivated vaccines are "killed" they have no ability to replicate, making this type of vaccine much safer than attenuated vaccines.

LONG-TERM IMMUNITY

Due to the nature of the viruses contained within attenuated vaccines, the immunity provided by this type of vaccine is typically long-term.

VS

NEEDS BOOSTERS

Due to the nature of the viruses contained within inactivated viruses, the immunity provided by this type of vaccine is relatively shorter and requires boosters to provide long term immunity.

THE TECHNOLOGY OF CHOICE

Regardless of the desired vaccine to be produce, VacciXcell's tidemotion bioreactor is your perfect partner. Tidemotion bioreactors are able to culture any type of adherent cell line used in virus production. The proprietary technology and linear scalability guarantees high virus titers while maintaining low operational and developmental costs.